For highly complex geometries or for parts with internal conformal cooling channels, produced by Powder Bed Fusion – Laser Beam (PBF-LB), the use of conventional post-processes is limited. The Hirtisation® process is an electro-chemical process, where the electrolyte can easily access both external and internal surfaces. The process has shown promising results in both support structure removal and surface enhancement, and has the potential to solve the productivity and quality trade-off in PBF-LB. In this study, we have investigated the role of the microstructure on the capability of the Hirtisation® process to enhance the PBF-LB produced surfaces. By detailed EBSD analysis of controlled microstructures the role of crystallographic orientation and grain size is studied in relation to the Hiritisation® process to evaluate on preferential regions of the process´s ability to remove material.