This comprehensive review delves into recent advancements in biomaterial surface engineering through the lens of three impactful studies employing Direct Laser Interference Patterning (DLIP). The first investigation explores the influence of processing parameters on zirconia surfaces using a 10 ps-pulsed laser. Optimal conditions were identified for creating homogeneous line-like patterns with varying feature sizes, demonstrating the versatility of DLIP in fabricating multi-scale topographic structures. The second part of the talk also extends the scope to functional zirconia surfaces, but employing a two-beam interference setup with a green ultra-short pulsed laser. By varying hatch distances, periodic structures were also successfully produced, showcasing the feasibility of DLIP in creating microtextures. Surface features were analyzed, revealing insights into the potential enhancement of hydrophobicity through DLIP on zirconia surfaces. The final investigation explores the application of DLIP on polyetheretherketone (PEEK) surfaces using an infrared ultra-short pulsed laser. The study provides a first insight into the influence of laser processing parameters on the production of multi-scale textured PEEK surfaces. Line-like structures with main and secondary structures were achieved, offering valuable perspectives for functionalizing PEEK surfaces through DLIP technology.