Laudatory Speaker: Dr. Heidi Goenaga Infante

Single-event ICP-mass spectrometry (SP-ICP-MS) is an already well-established method for micro/nano-particle (MNP) characterization for a variety of entities (e.g., nanoparticles, cells, or microplastics) [1]. Despite the outstanding evolution of the technique during the last decade, most studies still use the same approaches for signal evaluation and quantification, based on (1) the use of integrated intensity as the analytical signal and (2) the calculation of a transport efficiency (TE) coefficient. However, the increasing availability of MNP standards and advancements in hardware and software permit exploring new venues for MNP sizing, including TE-independent ones [2]. This presentation discusses alternative ways of calibration and quantification for single-event ICP-MS applications, highlighting their pros and cons as well as preferred areas of application.

References
[1] M. Resano, M. Aramendía, E. García-Ruiz, A. Bazo, E. Bolea-Fernandez, F. Vanhaecke, Chem. Sci., 2022, 13, 4436.
[2] A. Bazo, E. Bolea-Fernandez, A. Rua-Ibarz, M. Aramendía, M. Resano, Anal. Chim. Acta, 2024, 1331, 343305.