The present contribution addresses some aspects of multiscale modelling of powder bed fusion (PBF) processes. A thermomechanical macroscopic simulation framework based on the Finite Element (FE) method is introduced and exemplary analysis results and validations are discussed. In a first approach, the macroscopic thermal model of the PBF process is coupled to a phenomenological microstructure model to describe the spatially homogenized fractions of the beta-phase, the stable alpha phase and the martensitic alpha-phase for Ti-6Al-4V. The predictions of the model are compared to experimental results for a fir-tree-like structure. In a second method, the temperature field obtained by the macroscopic simulation approach are transferred to a cellular automaton (CA) method to predict the grain structure evolution of the Nickel alloy CMSX-4 during the manufacturing process. The grain structure evolution strongly depends on the temperature history computed during the process. The coupled FE-CA-approach is applied to model the properties of a cellular material additively manufactured of CMSX-4. The grain structure significantly influences the properties of the cellular material which is verified by means of computational homogenization. The cellular material is thereby modelled with geometrically exact beams and the material’s grain structure is taken into account by a crystal plasticity model.