MSE 2024
Poster
3D Printing of Gelatin-Base Porous Systems
FM

Filip Mikulka (M.Sc.)

Tomas Bata University in Zlín

Mikulka, F. (Speaker)¹; Minařík, A.¹; Musilová, L.¹
¹University of Tomas Bata in Zlín - Faculty of Technology

This work describes new types of 3D printable biocompatible materials based on gelatin to support cells adhesion and ensure their proliferation. The mechanical properties of pure gelatin are not suitable for additive manufacturing and it is necessary to improve them, for example by Shiff base cross-linking method. In the experiments, proteins (gelatin from different sources) was mixed with polysaccharide (oxidized dextran) in different ratios with the addition of activating agents (NH3 and TEA). The resulting material was then printed on a 3D bioprinter to the form of porous scaffolds. These scaffolds were subsequently subjected to porosity analysis in the native and lyophilized states using computed tomography. The results of cell proliferation tests suggest that the prepared scaffolds could serve as a supporting materials for tissue engineering applications

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