In this contribution the three-dimensional (3D) distribution and morphology of TCP phases in a single crystalline Ni-base superalloy manufactured by SEBM is studied with respect to mechanical response and precipitate-matrix interactions during micro-compression. For that purpose, micro-pillars on bulk support are extracted from a CMSX4 sample by laser ablation and subsequently polished by FIB-milling. By combining X-ray nanotomography and interrupted room temperature micro-compression the evolution of local strain within and around TCP phases is examined as function of global strain.