We show time-dependent degradation characteristics of silica particle-laden microgels and its correlated release kinetics of particles, by tuning the gel elasticity. In order to implement soft elastic matrices, the biodegradable microgels are fabricated based on the 3D network of gelatine chains. The gel matrix is designed to have strong autofluorescence, and the microgel elasticity is controlled by varying crosslinking degree. 3D printing technology is employed for fabricating microfluidic chips that are utilised for the synthesis and monitoring processes of microgels. The microgel size change and release amount of particles are monitored using time-lapse fluorescence microscopy, coupled with advanced image processing techniques.