Addressing mechanical damages is crucial for ensuring the longevity of materials. Nature's self-repair mechanism, inherent in biological systems, provides valuable insights for enhancing the resilience of engineering materials. This mechanism comprises two primary phases: self-sealing and self-healing. Leveraging the self-sealing mechanism, borrowed from living organisms, can be applied to engineer materials with improved durability. Bio-inspired self-sealing materials can be realized through the utilization of mechanical metamaterials, known for their exceptional mechanical properties derived from intricate inner structures that can be programmed to achieve specific functionalities. In this presentation, by inspiration of biological plant models, we introduce an innovative design of a mechanical metamaterial endowed with a programmable self-sealing function. The unit cells of this metamaterial respond to pressure changes caused by incoming damage, initiating a sequential process that propagates across adjacent unit cells, effectively closing cracks. To validate the functionality of the designed metamaterial, finite element simulations are undertaken to capture the nonlinearity and large deformation characteristics of a single unit cell. In addition, a comprehensive study of the self-sealing process was conducted across the entire metamaterial by introducing various cracks with different shapes and sizes and evaluating the effective self-sealing mechanism.