Interlocking meta-surfaces (ILMs) introduce a new class of mechanical metamaterials that enable programmable and reversible joining through engineered unit cells. These structures offer a tunable mechanical response, addressing key challenges in material compatibility, adaptability, and reusability. While prior studies have examined interfacial toughness (Young et al., 2024) and topological optimization (Brown et all., 2023) in constrained geometries, the role of unit cell architecture in governing interlocking behavior—particularly in vertical interlocking mechanisms—remains largely unexamined. This study develops a design framework for ILMs by systematically varying geometric parameters to tailor interlocking responses. Three distinct mechanical regimes emerge: (1) higher force required for locking than unlocking, (2) nearly equal forces for both, and (3) higher unlocking than locking forces. Furthermore, vertical interlocking mechanisms are investigated, demonstrating high structural integrity in compression-based applications, expanding ILMs beyond traditional sliding-based designs. Additionally, ILMs exhibit rate-dependent mechanical behavior, with interlocking forces increasing at higher displacement rates. Multi-scale tessellation studies confirm the scalability and integration potential of these structures in reconfigurable meta-architectures. These findings establish ILMs as a versatile platform for adaptive, material-independent joining technologies, with applications in robotics, aerospace, and morphing structures requiring controlled mechanical responses.