Our work presents a comprehensive investigation of the use of a hybrid material composed of two-dimensional (2D) MoS2 nanosheets and Ti-MIL-125 metal-organic-frameworks (MOFs) in photocatalytic hydrogen evolution reactions (HER) for sustainable hydrogen production from water splitting under UV-light. Ti-MIL-125 is a promising MOF for photocatalytic water splitting [1] and the MoS2 is here investigated as a non-noble HER co-catalyst, replacing the expensive benchmark Pt HER co-catalyst. MoS2 nanosheets and MIL-125 were synthesized by liquid phase exfoliation and solvothermal synthesis, respectively, then two simple methods were used to hybridize them. The resulting hybrid material was characterized using various techniques such as transmission electron microscopy, scanning electron microscopy, X-ray diffraction and UV-visible spectroscopy. The photocatalytic performance of the hybrid material was then evaluated. The results showed that hybridization resulted in remarkable HER performance, which was close to the performance values for benchmark Ti-MIL-125 with conventional Pt-co catalyst.