Simulation of casting and joining processes and experimental planning are closely related to liquid metallic materials’ thermophysical properties. Last thirty years, the experimental measurements of thermophysical properties together with the modelling of these properties represent on ground support for the measurements performed under microgravity conditions. Thermophysical properties datasets of Ni-based and Ti-based industrial alloys were analyzed through the application of experimental methods and theoretical models. In the present study, the model predicted values of the surface tension and viscosity of liquid Al-Ni and Al-Ti alloys were used to evaluate these properties of Al-Ni and Al-Ti multicomponent liquid alloys, estimating the effects of minor alloying components on the corresponding property. The calculated thermophysical properties values are related to the lower limit of estimation and with the available experimental datasets substantiate the reliability assessment of the two properties. In addition, the use of two or more models is useful for the constructing confidence intervals for predicted values that, combined with the experimental data obtained by different experimental methods, are necessary for data reliability assessment.