Welding process is one of the most important technology for attaching different materials in many industrial field. Many types of materials were used as welding material such as steel, aluminum, magnesium, titanium, copper, etc.. Although there were many welding techniques to weld dissimilar materials, the welding between dissimilar materials has risks of welding defect because of different material properties, especially thermal material properties. Most of the welding techniques uses heat during the welding process, so there are always has an issues about thermal defect such as heat affected zone, shrinkage, different melting point, etc.. Vaporizing Foil Actuator Welding process is one of the impact welding which uses vaporizing pressure of aluminum foil as a driving force of impact. In the VFAW process, two welding materials, which is called target sheet and flyer sheet, were collided with oblique angle by forming the metallic bonding between them. There is no external heat irradiation during the VFAW process, so the thermal defects in conventional welding is not considered in this process. Additionally, the sequential welding can be conducted using dissimilar materials likewise multi-layer materials because the thickness of target sheet is not restricted. It is possible to acquire functional traits by attaching dissimilar materials in many layers using sequential VFAW process. In this paper, various dissimilar materials such as Advanced High Strength Steel and aluminum were used for multi-layer VFAW process and the welding force and its material properties were estimated. Also, the effect of multi-layer welding from the respected to the functional materials such as high specific strength, elongation, and so on.