7th Euro BioMAT 2023 - European Symposium on Biomaterials and Related Areas
Lecture
04.05.2023 (CEST)
Development of a local drug delivery system for the cochlear implant
LS

Luisa Vanessa Steingrube (M.Sc.)

Leibniz Universität Hannover

Steingrube, L.V. (Speaker)¹; Baumgarten, J.¹; Behrens, P.¹; Goblet, M.²; Harre, J.²; Lenarz, T.²; Schierz, A.K.¹; Warnecke, A.²
¹Leibniz University Hannover; ²Medical School Hannover
Vorschau
14 Min. Untertitel (CC)

Hearing loss is associated with significant challenges in society. If deafness is caused by hair cell loss in the inner ear, a cochlear implant can partially restore hearing. One critical issue is the relatively large gap between the electrode and the spiral ganglion neurons that get stimulated. For that a growth factor-based drug delivery system will be installed on the cochlear electrode to reduce the distance. This system is built on nanoporous silica nanoparticles, neurotrophin 3, brain-derived neurotrophic factor, a polymer coating and silicone.

Abstract

Abstract

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