Optical diffusers are devices that scatter the incoming light into multiple wavefronts yielding diffuse illumination sources useful in photography, LED lighting, or liquid crystal displays. One strategy to produce highly diffusing optical components is patterning the surface of a transparent material with microfeatures so that the impinging light can be refracted and scattered into multiple angles. In this study, micro-structured polymethylmethacrylate (PMMA) diffusers are fabricated by combining different laser-based processes to produce metallic stamps with hot embossing for fast and cost-effective replication on the polymer. Namely, laser engraving (DLE), direct laser writing (DLW), and direct laser interference patterning (DLIP) methods were sequentially employed to pattern line- and dot-like arrays across different scales ranging from a few microns up to hundreds of microns. The fabricated single and hierarchical (with two and three hierarchy levels) textures are transferred to PMMA surfaces by plate-to-plate hot embossing at a controlled pressure and temperature. The dependence between the produced surface morphologies on the polymer foils and the optical performance is investigated using confocal and scanning electron microscopy as well as optical methods based on photospectroscopy and angular haze measurements. In general, significant increases of the diffuse transmittance in the visible spectrum were observed for all the micropatterned surfaces, reaching haze factors over 75% compared to 4% of the flat reference. To quantify the angular spread of the diffusers, the full width at half maximum (FWHM) of the angular intensity distribution was determined. Line-like patterns presented a strong anisotropic intensity characterized by FWHM values of up to 35° and 7° in directions perpendicular and parallel to the texture orientation, respectively. For pillar-like structures, a maximum FWHM of 24° was obtained for all angular directions. It was found that the triple-scaled surfaces exhibited a more homogeneous intensity distribution than single- or double-scaled structures. The strategy presented here represents a cost-effective alternative to conventional processes such as lithography, multiphoton polymerization, or direct laser writing of polymers for the production of hierarchical surfaces for optical diffusers.