Nanoplastics have emerged as a major environmental concern, infiltrating indoor air with their complex transport behavior and illusive elimination process, and posing severe health risks to humans. The rising concentration of micro-nano plastics in various environments, including the air we breathe, necessitates prompt action. Daily inhalation of up to 130 small plastic particles and fibers originating from clothing and other sources has been associated with pulmonary inflammation, lung cancer, and other diseases. We devised the ground-breaking DTA (detect, capture, adsorb) technology in response to this critical issue. Commercial air purifiers are unable to regulate micro-nano plastics in indoor air due to their inefficiency and limitations. Our innovative technology incorporates intelligent sensors for detecting airborne micro-nano plastics as a first step. To overcome this obstacle, we employ extremely effective porous materials, such as metal-organic frameworks, covalent organic frameworks (Cr-MOF, ZIF-67, ZIF-8, and COFs (TpPa-X, X = H, CH3, OH, NO2, and F), and magnetic nanomaterials such as MeXene-derived Fe2O3/Pt/TiO2. These materials feature distinctive properties that allow for the efficient absorption and capture of micro-nano plastics. We utilize state-of-the-art materials in combination with different polymers such as polyimide (PI), polyurethane (PUR), polyacrylonitrile (PAN), polyamide-66 (PA-66), polyamide-56 (PA-56), and polysulfone (PSF) to create air filters that specifically target the removal of micro-nano plastic particles. These filters are manufactured using the electrospinning technique. The resultant air purifier provides a robust method for combating the presence of micro-nano plastics in indoor environments. Our technology, which is currently undertaking rigorous testing, promises to defend human health from the detrimental effects of micro- and nano-plastics. By implementing this innovative strategy, we hope to address the urgent problem of indoor nano-plastic pollution and contribute to the well-being of people around the world. This study emphasizes the significance of the issue, underlines the innovative aspects of our proposed technology, and describes the potential advantages of its implementation. In addition, our future research intends to concentrate on materials engineering, with the development of novel porous materials that not only capture micro-nano plastics but also have self-cleaning properties, allowing for degradation. By revolutionizing the fight against nano-plastic pollution, Our DTA technology offers a promising way for developing a healthier and cleaner indoor environment.