Biofilm formation, in this case, dental biofilm formation, is a complex phenomenon involving biopolymers and microorganisms. The first step is the formation of a conditioning film by non-specific adsorption of non-microbial components that microbes will, later on, colonize [1]. Two main components of the conditioning film are proteins and carbohydrates. Here, the adsorption of important salivary proteins (bovine serum albumin (BSA), lysozyme (LYS)) and a polysaccharide (dextran, DEX) on dental titanium have been investigated by a multimethod approach comprising biochemical assays (protein [2] and carbohydrate [3] amounts, lysozyme activity) and surface analytical methods (scanning force microscopy and spectroscopy, and quartz crystal microbalance). Furthermore, a UV spectrophotometric quantification method was developed to simultaneously determine the total amounts of proteins and polysaccharides in the same sample. [4]