A surface functionalization of materials in order to improve their haemocompatibility is a challenging problem in the field of blood-contacting devices and implants. The Polyelectrolyte Multilayer Films (PEMs), which can mimic functions and structure of an extracellular matrix (ECM), a natural tissue scaffold, seem to be one of a promising solutions to the urgent need for the novel blood-contacting coatings. The properties of PEMs can be easily tuned in order to provide scaffold with a desired physico-chemical parameters. In this work, films were manufactured using chitosan and chondroitin sulphate (Chi/CS) in  24 bilayers configuration. Coatings deposition was conducted using Layer-by-Layer method through automatic dipping machine. Such multilayers were modified by silicon carbide (SiC) and amorphous hydrogenated carbon (a-C:H:N).